Evaluation of Acute Toxicity, Antioxidant and Antibacterial Potential of Leaves Extracts from Two Anacardiaceae’s Species: <i>Lannea microcarpa</i> Engl. & K. Krause and <i>Mangifera indica</i> L.

Background: Leaves of Mangifera indica L or Lannea microcarpa Engl. & K. Krause are used in traditional medicine Burkina Faso to treat bacterial, parasitic metabolic diseases. Objective: The aim this study is evaluate the acute general toxicity, antioxidant potential and antibacterial activitiy leave’s aqueous extracts from L. use these plants motivated our choice lead scientific studies. Methods: decoction leaves form recommended by healers. We same type for Acute toxicity was studied NMRI strain mice, with dose 2000 mg/kg body weight, each plant species. activity evaluated method reduction radical DPPH. phytochemical compounds were detected specific reagent: Alcaloids Dragendorff’s reagent, Flavonoids ammonia (NH4OH), Polyphenols tannins revelated ferric chloride (FeCl3). Saponosides their foaming power property. Bacterial inhibiting tested measuring diameters’ inhibition on reference strains. Results: not toxic at maximum showed an IC50, 20 μg/ml 18 indica. no bacterial three strains bacteria tested: Escherichia coli, Pseudomonas aeruginosa Staphylococcus aureus. phytochemicals we have identified microcarpa: phenolics compounds, triterpenes, saponosides. M. indica’s extracts: saponosides flavonoids.